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Year : 2021  |  Volume : 45  |  Issue : 3  |  Page : 122-127

Malignant transformation of a mature teratoma with concurrent cervical carcinoma versus squamous cell carcinoma of the cervix with ovarian metastasis: A diagnostic dilemma

Department of Obstetrics and Gynecology, Jose B. Lingad Memorial Regional Hospital, City of San Fernando, Pampanga, Philippines

Correspondence Address:
Ina Felize A. Ramajo
Philippine Obstetrical and Gynecological Society, Jose B. Lingad Memorial General Hospital
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Source of Support: None, Conflict of Interest: None

DOI: 10.4103/pjog.pjog_15_21

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Mature cystic teratoma of the ovary may occur in 10%–20% of women during their lifetime. Its biological behavior is benign, while 0.17%–2% of them may undergo malignant transformation. Various histological types of malignant transformation include Squamous cell carcinoma (SCC), adenocarcinoma, small cell carcinoma, sarcoma, malignant melanoma, and mixed histology. SCCA of the cervix occurs more commonly at ages 45–55. This is mainly caused by human papillomavirus 16 and 18. This tumor spreads to local then regional lymph nodes and can have hematogenous spread to bone and lungs, rarely to the ovaries. This report is of a 75-year-old Gravida 9 Para 9 (9009) with an enlarging pelviabdominal mass, managed as a case of ovarian new growth with later findings of cervical cancer. The case merits presentation because of the dilemma in diagnosis.

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