• Users Online: 216
  • Print this page
  • Email this page
Year : 2022  |  Volume : 46  |  Issue : 2  |  Page : 85-90

More than teen angst: A case of ovarian teratoma presenting as anti-N-methyl-d-aspartate receptor encephalitis

Department of Obstetrics and Gynecology, Institute for Women's Health, The Medical City, Pasig City, Philippines

Correspondence Address:
Ma Rosila F. Escudero
Department of Obstetrics and Gynecology, Institute of Women's Health, The Medical City, Ortigas Avenue, Pasig City
Login to access the Email id

Source of Support: None, Conflict of Interest: None

DOI: 10.4103/pjog.pjog_18_22

Rights and Permissions

A 17-year-old nulligravid presented with labile mood, insomnia, and hyper-productive speech for 2 days, which progressed to seizures. Cerebrospinal fluid was positive for anti-N-methyl-d-aspartate (NMDA) receptor antibodies. Despite immunotherapy and seizure prophylaxis, she had status epilepticus and rapid decrease in sensorium. She was placed on ventilatory support and was admitted in the intensive care unit. On the 44th hospital day, an incidental finding of an ovarian teratoma was seen on abdominal computed tomography scan. She underwent right salpingo-oophorectomy, which revealed an immature teratoma. The absence of an intensive care admission and prompt surgery and immunotherapy are known predictors of good outcome in anti-NMDA receptor (NMDAR) encephalitis, with improvement seen in 80% of patients. Because most ovarian teratomas are only diagnosed as an incidental finding, anti-NMDAR encephalitis with a concurrent ovarian teratoma should be suspected in young females presenting with sudden-onset neuropsychiatric symptoms, to provide the timely intervention necessary for a good prognosis.

Print this article     Email this article
 Next article
 Previous article
 Table of Contents

 Similar in PUBMED
   Search Pubmed for
   Search in Google Scholar for
 Related articles
 Citation Manager
 Access Statistics
 Reader Comments
 Email Alert *
 Add to My List *
 * Requires registration (Free)

 Article Access Statistics
    PDF Downloaded63    
    Comments [Add]    

Recommend this journal