Philippine Journal of Obstetrics and Gynecology

CASE REPORT
Year
: 2021  |  Volume : 45  |  Issue : 4  |  Page : 160--164

A series of missing primaries: Pulmonary metastasis in Gestational Trophoblastic Neoplasia in the absence of uterine tumors


Gillian Patrick C. Gonzalez, Agnes L Soriano-Estrella 
 Division of Trophoblastic Diseases, Department of Obstetrics and Gynecology, Philippine General Hospital, University of the Philippines, Manila, Philippines

Correspondence Address:
Gillian Patrick C. Gonzalez
MD, Department of Obstetrics and Gynecology, Philippine General Hospital, University of the Philippines, Manila
Philippines

Gestational trophoblastic neoplasias (GTN) are extremely aggressive tumors derived from placental trophoblasts. These tumors are always the sequalae of a pregnancy. Choriocarcinoma, which is the most common of these, is typically characterized by early extra-pelvic hematogenous spread. Since the progression of illness is rapid, timely diagnosis and treatment will favor improved chances for cure, whereas late commencement of therapy will make resolution difficult. The diagnosis of GTN is straightforward with an elevated beta-human chorionic gonadotropin (β-hCG) and distinct sonographic features of the tumor inside the uterus. However, very rarely, this disease may occur in the absence of uterine tumors. Practicing physicians must be mindful that GTN may initially manifest with pulmonary symptoms and/or radiographic evidence of metastatic lung lesions. In this series, the features pertaining to the clinical course of three patients are described, all of whom presented with pulmonary masses, elevated β-hCG, and normal transvaginal sonograms.


How to cite this article:
Gonzalez GP, Soriano-Estrella AL. A series of missing primaries: Pulmonary metastasis in Gestational Trophoblastic Neoplasia in the absence of uterine tumors.Philipp J Obstet Gynecol 2021;45:160-164


How to cite this URL:
Gonzalez GP, Soriano-Estrella AL. A series of missing primaries: Pulmonary metastasis in Gestational Trophoblastic Neoplasia in the absence of uterine tumors. Philipp J Obstet Gynecol [serial online] 2021 [cited 2022 Jan 19 ];45:160-164
Available from: https://www.pogsjournal.org/article.asp?issn=0116-6069;year=2021;volume=45;issue=4;spage=160;epage=164;aulast=Gonzalez;type=0