Philippine Journal of Obstetrics and Gynecology

CASE REPORT
Year
: 2021  |  Volume : 45  |  Issue : 4  |  Page : 165--170

Primary pulmonary epithelioid trophoblastic tumor co-existing with choriocarcinoma


Elizabeth K Jacinto1, Jose Ma C. Avila2 
1 Division of Trophoblastic Diseases, Department of Obstetrics and Gynecology, Philippine General Hospital, University of the Philippines, Manila, Philippines
2 Department of Pathology, Philippine General Hospital, University of the Philippines, Manila, Philippines

Correspondence Address:
Elizabeth K Jacinto
MD. Associate Professor, Department of Obstetrics and Gynecology, Philippine General Hospital, University of the Philippines, Manila
Philippines

A 28-year old, G5P4 (4014), noted neck lymph nodes associated with cough. A chest X-ray was done showing a left nodular opacity. Antibiotics were prescribed with a resolution of symptoms. Five months after, a routine chest X-ray revealed interval progression in size of the lung nodule. A chest computed tomography (CT) scan and positron-emission tomography scan were done subsequently showing the precise location and size of the nodule and with no other focus of tumor seen. Transvaginal ultrasound was normal. With an initial diagnosis of lung carcinoma, a percutaneous needle aspiration biopsy under CT scan guidance was done. Immunohistochemical staining panel showed that beta-human chorionic gonadotropin (hCG) was positive. Subsequently, a serum beta-hCG done showed low levels from 33.48 to 59.7 mIU/ml. The final diagnosis given was a poorly differentiated malignancy highly suggestive of malignant trophoblastic tumor. A video-assisted left upper lobectomy was performed with histopathology and immunohistochemistry consistent with epithelioid trophoblastic tumor with co-existing choriocarcinoma elements. Postoperative beta-hCG level dropped to normal and remained so for 2½ years.


How to cite this article:
Jacinto EK, Avila JM. Primary pulmonary epithelioid trophoblastic tumor co-existing with choriocarcinoma.Philipp J Obstet Gynecol 2021;45:165-170


How to cite this URL:
Jacinto EK, Avila JM. Primary pulmonary epithelioid trophoblastic tumor co-existing with choriocarcinoma. Philipp J Obstet Gynecol [serial online] 2021 [cited 2022 Jan 19 ];45:165-170
Available from: https://www.pogsjournal.org/article.asp?issn=0116-6069;year=2021;volume=45;issue=4;spage=165;epage=170;aulast=Jacinto;type=0